Characteristics of the _E. coli Genome

• The Origin of DNA Replication (oriC) is not at position zero (0°)!
  • In E. coli B REL606: approximately 3,885,994–3,886,373
  • In E. coli K12 MG1655: 3,923,767–3,923,998 EcoCyc
• Termination of DNA replication occurs between Ter sites EcoCyc
  • The innermost Ter sites are near the manA and trp genes
    See Fig. 1 of Neylon2005
  • In E. coli B REL606: approximately between 1,320,676–1,665,771
• Resolution of the chromosome copies after replication occurs at the Dif site
  • In E. coli B REL606: approximately 1,567,103–1,567,421
  • In E. coli K12 MG1655:1,588,774-1,588,801