Acinetobacter baylyi ADP1 quick reference

Antibiotic/toxin resistance

Antibiotic MIC Standard Conc. Status Notes
Ampicillin (or carbenicillin) 128 g/ml 100 g/ml Resistant  
Spectinomycin ? 60 g/ml Sensitive  
Streptomycin 6.25-12.5 g/ml (escapes observed at 6.25g/mL) 25 g/ml Sensitive Barrick Lab results (G.S.)
Kanamycin 12.5-6.25g/ml (3.125g/mL doesn't inhibit) 50 g/ml Sensitive MIC info from Barrick Lab results (G.S.)
Chloramphenicol 4.0 g/ml 20 g/ml Sensitive Spontaneous resistance
Gentamycin 1.3 g/ml 5 g/ml Sensitive  
Tetracycline 1.0 g/ml 10 g/ml Sensitive  
Rifampicin 0.6 g/ml 100 g/ml Sensitive Spontaneous resistance
Nalidixic acid (mutagen/causes DNA double strand breaks) 1.9g/mL (no growth at 24hr, but growth at 48hr) (1g/mL doesn't inhibit) 3.75 g/ml Sensitive Barrick Lab results (G.S.)

Note: ΔacrB (ACIAD2944) makes more susceptible to multiple antibiotics.

Source: Gomez MJ, Neyfakh AA. (2006) Genes involved in intrinsic antibiotic resistance of Acinetobacter baylyi. Antimicrob Agents Chemother 50:3562–3567.

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Topic revision: r6 - 24 Feb 2017 - 21:34:25 - Main.GabrielSuarez
 
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