breseq  version 0.26.1  
mutation predictions | marginal predictions | summary statistics | genome diff | command line log

Predicted mutations
evidence position mutation freq annotation gene description
RA 9,972 T→G 40.1% N174T (AAC→ACC)  yaaH ← conserved inner membrane protein associated with acetate transport
JC JC 16,990 IS150 (+) +3 bp 100% intergenic (‑32/‑496) mokC ← / → nhaA regulatory protein for HokC, overlaps CDS of hokC/pH‑dependent sodium/proton antiporter
RA 200,540 C→T 5.9% L385F (CTT→TTT)  yaeL → zinc metallopeptidase
RA 281,923 G→T 93.3% intergenic (‑406/‑369) ykgK ← / → ykgL predicted regulator/hypothetical protein
RA 473,901 +C 46.7% coding (1405/1677 nt) ybaL ← predicted transporter with NAD(P)‑binding Rossmann‑fold domain
RA 473,901 +G 46.7% coding (1405/1677 nt) ybaL ← predicted transporter with NAD(P)‑binding Rossmann‑fold domain
JC JC 546,191 IS1 (+) +9 bp 100% coding (346‑354/384 nt) ybcQ → predicted antitermination protein
MC JC 547,700 Δ2,651 bp 100% IS1‑mediated [nmpC][ybcU] [nmpC], ybcR, ybcS, ybcT, [ybcU]
JC JC 643,362 IS150 (+) +3 bp 43.3% coding (598‑600/954 nt) ybeF ← predicted DNA‑binding transcriptional regulator
RA 648,692 C→T 100% R69H (CGC→CAC)  mrdB ← cell wall shape‑determining protein
RA 737,252 C→A 4.2% I185I (ATC→ATA sdhA → succinate dehydrogenase flavoprotein subunit
JC JC 1,162,790 IS150 (–) +3 bp 41.7% coding (601‑603/1071 nt) plsX → fatty acid/phospholipid synthesis protein
RA 1,331,794 C→A 100% T792K (ACG→AAG)  topA → DNA topoisomerase I
JC JC 1,420,709 +GA :: IS3 (+) +4 bp 14.6% intergenic (+21/‑9) ynaK → / → ECB_01341 conserved protein/hypothetical protein
JC JC 1,462,320 IS150 (–) +3 bp 90.4% intergenic (‑82/‑257) mokB ← / → trg regulatory peptide/methyl‑accepting chemotaxis protein III, ribose and galactose sensor receptor
RA 1,607,916 Δ1 bp 36.1% coding (17/1320 nt) ECB_01510 ← putative tail component of prophage
JC JC 1,648,342 IS1 (–) +9 bp 28.2% intergenic (+195/‑221) ynfM → / → asr predicted transporter/acid shock protein precursor
RA 1,691,510 G→A 36.0% intergenic (+45/‑61) ydgR → / → gst putative tripeptide transporter permease/glutathionine S‑transferase
RA 1,733,343 G→A 100% D127N (GAT→AAT)  pykF → pyruvate kinase
JC JC 1,776,434 IS150 (–) +4 bp 56.9% intergenic (‑225/+56) pheS ← / ← pheM phenylalanyl‑tRNA synthetase alpha subunit/phenylalanyl‑tRNA synthetase operon leader peptide
RA 1,805,203 C→A 14.0% V108L (GTA→TTA)  astB ← succinylarginine dihydrolase
JC JC 2,122,426 IS150 (–) +3 bp 46.2% coding (198‑200/216 nt) ECB_02013 ← conserved hypothetical protein; putative exported protein
RA 2,333,538 +T 100% intergenic (+34/+34) ECB_02200 → / ← nuoN YadA protein/NADH dehydrogenase subunit N
RA 2,446,984 A→C 100% intergenic (‑53/‑283) mntH ← / → nupC manganese transport protein MntH/nucleoside (except guanosine) transporter
JC JC 2,448,493 IS186 (+) +6 bp 66.5% intergenic (+24/+21) nupC → / ← yfeA nucleoside (except guanosine) transporter/predicted diguanylate cyclase
RA 2,665,639 A→T 92.4% L100Q (CTG→CAG)  rplS ← 50S ribosomal protein L19
RA 2,999,330 G→A 100% intergenic (+138/‑234) yeeP → / → flu b1999; predicted GTP‑binding protein/antigen 43 (Ag43) phase‑variable biofilm formation autotransporter
JC JC 3,015,771 IS150 (–) +3 bp 97.6% coding (1192‑1194/1677 nt) ECB_02816 → KpsD protein
RA 3,152,406 A→C 21.7% K41N (AAA→AAC ygjG → putrescine:2‑oxoglutaric acid aminotransferase, PLP‑dependent
RA 3,183,348 G→A 32.6% G80S (GGC→AGC)  yqjK → hypothetical protein
RA 3,249,829 C→A 7.2% G474C (GGT→TGT)  infB ← translation initiation factor IF‑2
JC JC 3,268,052 IS150 (+) +3 bp 55.8% intergenic (‑83/+42) yhbE ← / ← rpmA conserved inner membrane protein/50S ribosomal protein L27
RA 3,339,313 A→C 100% Y51S (TAT→TCT)  fis → DNA‑binding protein Fis
RA 3,401,754 C→A 100% R78L (CGC→CTC)  rpsG ← 30S ribosomal protein S7
JC JC 3,454,489 IS150 (+) +4 bp 38.1% coding (342‑345/561 nt) yrfE ← ADP‑ribose diphosphatase
RA 3,463,900 C→T 48.4% R218H (CGC→CAC)  envZ ← osmolarity sensor protein
RA 3,475,057 C→T 36.6% intergenic (+193/‑168) yhgI → / → gntT predicted gluconate transport associated protein/gluconate transporter, high‑affinity GNT I system
RA 3,481,820 A→G 100% T46A (ACC→GCC)  malT → transcriptional regulator MalT
RA 3,488,669 A→C 47.7% S180A (TCG→GCG)  glpR ← DNA‑binding transcriptional repressor
JC JC 3,517,306 IS186 (+) +8 bp :: Δ2 56.2% coding (187‑194/1743 nt) ggt ← gamma‑glutamyltranspeptidase periplasmic precursor
RA 3,670,539 A→C 3.6% K127Q (AAA→CAA)  avtA → valine‑pyruvate transaminase
RA 3,893,550 Δ1 bp 29.5% intergenic (+5/‑51) kup → / → insJ‑5 potassium transporter/IS150 hypothetical protein
RA 3,893,550 +G 4.7% intergenic (+5/‑51) kup → / → insJ‑5 potassium transporter/IS150 hypothetical protein
MC JC 3,894,997 Δ6,460 bp 100% IS150‑mediated rbsD[yieO] rbsD, rbsA, rbsC, rbsB, rbsK, rbsR, [yieO]
RA 3,909,807 G→T 100% intergenic (‑40/‑79) hdfR ← / → yifE transcriptional regulator HdfR/hypothetical protein
RA 4,100,183 A→G 100% S350P (TCT→CCT)  hslU ← ATP‑dependent protease ATP‑binding subunit
RA 4,107,018 T→A 48.2% P123P (CCA→CCT ECB_03822 ← putative outer membrane lipoprotein
JC JC 4,110,237 IS150 (–) +3 bp 100% coding (296‑298/2433 nt) metL → bifunctional aspartate kinase II/homoserine dehydrogenase II
RA 4,111,342 C→T 48.3% G467G (GGC→GGT metL → bifunctional aspartate kinase II/homoserine dehydrogenase II
RA 4,201,958 A→C 46.0% L201R (CTC→CGC)  iclR ← DNA‑binding transcriptional repressor
RA 4,202,088 C→T 5.0% A158T (GCT→ACT)  iclR ← DNA‑binding transcriptional repressor
RA 4,335,105 C→A 9.5% A9A (GCG→GCT yjdL ← predicted transporter
RA 4,363,338 C→A 11.5% G263G (GGC→GGA yjeM → predicted transporter
RA 4,431,394 Δ2 bp 100% coding (3526‑3527/3780 nt) ytfN → hypothetical protein
JC JC 4,524,522 IS186 (+) +6 bp 94.5% coding (494‑499/549 nt) fimA → major type 1 subunit fimbrin (pilin)
RA 4,606,814 G→A 3.7% A86A (GCG→GCA deoC → deoxyribose‑phosphate aldolase
JC JC 4,613,019 +TT :: IS150 (+) 100% intergenic (‑16/‑91) smp ← / → serB hypothetical protein/3‑phosphoserine phosphatase
RA 4,616,538 A→C 94.2% Y337S (TAC→TCC)  nadR → nicotinamide‑nucleotide adenylyltransferase
RA 4,621,349 C→A 5.8% intergenic (+50/+35) trpR → / ← yjjX Trp operon repressor/NTPase

Unassigned missing coverage evidence
   seq id start end size ←reads reads→ gene description
* * ÷ REL606 1270058–1270154 1270659–1270418 265–602 49 [45] [1] 171 ldrC ldrC
* * ÷ REL606 4017655–4017755 4017997–4017764 10–343 52 [41] [46] 52 rrlA 23S ribosomal RNA

Unassigned new junction evidence...
  seq id position reads (cov) reads (cov) score skew freq annotation gene product
* ? REL606 = 9903115 (1.120)22 (0.220) 8/46 NT 23.0% intergenic (+12/+23) mogA/yaaH molybdenum cofactor biosynthesis protein/conserved inner membrane protein associated with acetate transport
?REL606 = 1095351 37 (0.380)intergenic (‑185/‑238) putA/putP fused DNA‑binding transcriptional regulator/proline dehydrogenase/pyrroline‑5‑carboxylate dehydrogenase/proline:sodium symporter
* ? REL606 = 9904112 (1.090)9 (0.100) 5/42 NT 11.5% intergenic (+13/+22) mogA/yaaH molybdenum cofactor biosynthesis protein/conserved inner membrane protein associated with acetate transport
?REL606 4001993 = 40 (0.440)intergenic (+10/‑32) tatC/tatD TatABCE protein translocation system subunit/DNase, magnesium‑dependent
* ? REL606 10617 =104 (1.010)21 (0.220) 7/44 NT 21.3% intergenic (‑125/+24) yaaH/yaaW conserved inner membrane protein associated with acetate transport/hypothetical protein
?REL606 = 3622975 60 (0.640)coding (1754/2619 nt) yhjO cellulose synthase, catalytic subunit
* ? REL606 13453 =80 (0.780)8 (0.080) 4/44 NT 10.6% coding (1293/1917 nt) dnaK molecular chaperone DnaK
?REL606 348289 = 62 (0.660)coding (475/1212 nt) mhpT predicted 3‑hydroxyphenylpropionic transporter
* ? REL606 32485 =59 (0.570)7 (0.070) 6/46 NT 12.4% coding (40/822 nt) dapB dihydrodipicolinate reductase
?REL606 = 671859 42 (0.430)coding (1118/1539 nt) lnt apolipoprotein N‑acyltransferase
* ? REL606 = 42237147 (1.430)9 (0.100) 4/42 NT 5.9% pseudogene (740/885 nt) caiB crotonobetainyl‑CoA:carnitineCoA‑transferase; b0038_1
?REL606 2742547 = 160 (1.780)coding (1555/1827 nt) hycC NADH dehydrogenase subunit N
* ? REL606 = 4798785 (0.830)13 (0.280) 4/22 NT 25.8% coding (605/942 nt) fixB predicted electron transfer flavoprotein, NAD/FAD‑binding domain and ETFP adenine nucleotide‑binding domain‑like
?REL606 1306336 = 36 (0.760)intergenic (‑97/+274) cls/kch cardiolipin synthetase/voltage‑gated potassium channel
* ? REL606 = 5007864 (0.620)8 (0.100) 3/38 NT 17.8% coding (77/1332 nt) yaaU predicted transporter
?REL606 558256 = 23 (0.280)coding (193/294 nt) ECB_00516 conserved hypothetical protein
* ? REL606 76423 =43 (0.420)4 (0.050) 3/36 NT 7.3% coding (903/1611 nt) thiP thiamin ABC transporter membrane protein
?REL606 = 3891004 69 (0.900)coding (451/1497 nt) yieN fused predicted transcriptional regulator: sigma54 activator protein/conserved protein
* ? REL606 82013 =70 (0.680)10 (0.160) 3/30 NT 19.5% coding (245/606 nt) leuD isopropylmalate isomerase small subunit
?REL606 3792209 = 39 (0.610)coding (315/414 nt) ECB_03532 hypothetical protein
* ? REL606 = 10868572 (0.700)24 (0.310) 8/36 NT 29.3% coding (577/1152 nt) ftsZ cell division protein FtsZ
?REL606 = 2243652 62 (0.800)coding (1242/1944 nt) ccmF heme lyase, CcmF subunit
* ? REL606 114196 =59 (0.570)12 (0.130) 3/42 NT 17.6% coding (349/390 nt) mutT nucleoside triphosphate pyrophosphohydrolase, marked preference for dGTP
?REL606 422596 = 61 (0.680)intergenic (‑283/+179) cyoA/ampG cytochrome o ubiquinol oxidase subunit II/muropeptide transporter
* ? REL606 140702 =57 (0.550)10 (0.130) 3/36 NT 18.6% coding (817/1551 nt) cueO multicopper oxidase (laccase)
?REL606 1349560 = 45 (0.580)intergenic (‑152/+216) fabI/ycjD enoyl‑(acyl carrier protein) reductase/hypothetical protein
* ? REL606 180751 =70 (0.680)8 (0.080) 5/46 NT 13.4% coding (554/801 nt) yadT vitamin B12‑transporter protein BtuF
?REL606 3966540 = 36 (0.370)intergenic (‑56/‑97) ECB_03694/ECB_03695 conserved hypothetical protein/Magnesium and cobalt transport protein corA
* ? REL606 187382 =110 (1.070)13 (0.150) 3/40 NT 14.9% coding (530/813 nt) yaeI predicted phosphatase
?REL606 3669194 = 57 (0.670)coding (1242/2031 nt) malS periplasmic alpha‑amylase precursor
* ? REL606 197679 =131 (1.270)16 (0.200) 5/38 NT 15.6% intergenic (+120/‑66) ispC/uppS 1‑deoxy‑D‑xylulose 5‑phosphate reductoisomerase/undecaprenyl pyrophosphate synthase
?REL606 2304413 = 69 (0.850)coding (802/903 nt) yfaD hypothetical protein
* ? REL606 207313 =39 (0.380)6 (0.060) 3/44 NT 6.9% coding (1124/1149 nt) lpxB lipid‑A‑disaccharide synthase
?REL606 1513006 = 126 (1.340)coding (3736/3741 nt) narZ nitrate reductase 2 (NRZ), alpha subunit
* ? REL606 212468 =63 (0.610)18 (0.200) 5/42 NT 18.6% intergenic (+46/‑53) accA/ldcC acetyl‑CoA carboxylase subunit alpha/lysine decarboxylase 2, constitutive
?REL606 235476 = 117 (1.140)intergenic (+3/+45) yafE/mltD predicted S‑adenosyl‑L‑methionine‑dependent methyltransferase/predicted membrane‑bound lytic murein transglycosylase D
* ? REL606 = 21877970 (0.680)12 (0.160) 4/36 NT 15.1% coding (669/711 nt) cutF lipoprotein involved with copper homeostasis and adhesion
?REL606 4525951 = 82 (1.060)intergenic (+8/‑59) fimC/fimD chaperone, periplasmic/outer membrane usher protein, type 1 fimbrial synthesis
* ? REL606 223959 =46 (0.450)15 (0.180) 4/38 NT 24.3% coding (503/654 nt) metI DL‑methionine transporter subunit
?REL606 1306336 = 57 (0.700)intergenic (‑97/+274) cls/kch cardiolipin synthetase/voltage‑gated potassium channel
* ? REL606 225795 =119 (1.160)11 (0.130) 3/40 NT 13.7% coding (123/573 nt) gmhB hypothetical protein
?REL606 2126049 = 40 (0.470)coding (187/1041 nt) gatD galactitol‑1‑phosphate dehydrogenase, Zn‑dependent and NAD(P)‑binding
* ? REL606 = 246042115 (1.120)8 (0.080) 5/44 NT 10.0% coding (1833/2445 nt) fadE acyl‑CoA dehydrogenase
?REL606 503801 = 39 (0.410)coding (587/927 nt) ybbS DNA‑binding transcriptional activator of the allD operon
* ? REL606 255937 =63 (0.610)13 (0.150) 7/40 NT 22.5% coding (477/1056 nt) dinB DNA polymerase IV
?REL606 3367494 = 37 (0.430)intergenic (‑80/+27) yhdN/rplQ hypothetical protein/50S ribosomal protein L17
* ? REL606 = 25693370 (0.680)10 (0.130) 4/36 NT 13.6% coding (70/399 nt) yafO predicted toxin of the YafO‑YafN toxin‑antitoxin system
?REL606 3944634 = 75 (0.970)intergenic (+23/‑124) proM/aslB tRNA‑Pro/predicted regulator of arylsulfatase activity
* ? REL606 = 28073259 (0.570)9 (0.120) 3/36 NT 14.3% coding (170/636 nt) yagZ hypothetical protein
?REL606 3006460 = 64 (0.830)coding (470/819 nt) yafZ conserved protein
* ? REL606 285065 =85 (0.830)8 (0.120) 3/30 NT 14.3% coding (529/4257 nt) eaeH attaching and effacing protein, pathogenesis factor
?REL606 = 3978905 43 (0.670)coding (1426/2262 nt) metE 5‑methyltetrahydropteroyltriglutamate‑ homocysteine methyltransferase
* ? REL606 = 29354872 (0.700)8 (0.090) 5/42 NT 9.4% coding (673/855 nt) ykgD predicted DNA‑binding transcriptional regulator
?REL606 2499664 = 92 (1.020)coding (171/951 nt) talA transaldolase A
* ? REL606 293737 =51 (0.500)8 (0.090) 4/40 NT 11.3% intergenic (+7/‑520) ykgD/ykgE predicted DNA‑binding transcriptional regulator/predicted oxidoreductase
?REL606 = 1036069 83 (0.970)intergenic (+41/+35) ycbG/ompA hypothetical protein/outer membrane protein A (3a;II*;G;d)
* ? REL606 294203 =75 (0.730)12 (0.160) 3/36 NT 18.3% intergenic (+473/‑54) ykgD/ykgE predicted DNA‑binding transcriptional regulator/predicted oxidoreductase
?REL606 836230 = 51 (0.660)coding (1876/2226 nt) ybiO predicted mechanosensitive channel
* ? REL606 294204 =76 (0.740)6 (0.070) 3/38 NT 10.8% intergenic (+474/‑53) ykgD/ykgE predicted DNA‑binding transcriptional regulator/predicted oxidoreductase
?REL606 = 2574914 39 (0.480)intergenic (+756/+62) sseA/sseB 3‑mercaptopyruvate sulfurtransferase/rhodanase‑like enzyme, sulfur transfer from thiosulfate
* ? REL606 312869 =100 (0.970)13 (0.150) 6/40 NT 13.5% coding (56/951 nt) yahI predicted carbamate kinase‑like protein
?REL606 4351443 = 83 (0.970)intergenic (+51/‑87) groEL/yjeI chaperonin GroEL/hypothetical protein
* ? REL606 = 31308524 (0.230)4 (0.040) 3/48 NT 6.4% coding (272/951 nt) yahI predicted carbamate kinase‑like protein
?REL606 = 661462 93 (0.910)intergenic (+13/+47) ybeV/hscC Hsc56 co‑chaperone of HscC/Hsp70 family chaperone Hsc62, binds to RpoD and inhibits transcription
* ? REL606 326204 =101 (0.980)10 (0.130) 4/36 NT 14.1% coding (849/1887 nt) prpE predicted propionyl‑CoA synthetase with ATPase domain
?REL606 = 4116137 46 (0.600)intergenic (+15/‑78) katG/yijE catalase/hydroperoxidase HPI(I)/predicted permease
* ? REL606 326209 =90 (0.880)5 (0.050) 3/46 NT 7.2% coding (854/1887 nt) prpE predicted propionyl‑CoA synthetase with ATPase domain
?REL606 3368427 = 42 (0.430)coding (508/990 nt) rpoA DNA‑directed RNA polymerase subunit alpha
* ? REL606 327441 =112 (1.090)14 (0.140) 5/48 NT 14.4% intergenic (+199/‑37) prpE/codB predicted propionyl‑CoA synthetase with ATPase domain/cytosine transporter
?REL606 1238616 = 54 (0.530)coding (896/1299 nt) dadA D‑amino acid dehydrogenase small subunit
* ? REL606 = 35781079 (0.770)3 (0.040) 3/36 NT 3.8% coding (826/975 nt) hemB delta‑aminolevulinic acid dehydratase
?REL606 = 357826 94 (1.220)coding (810/975 nt) hemB delta‑aminolevulinic acid dehydratase
* ? REL606 365501 =115 (1.120)5 (0.060) 3/40 NT 6.1% coding (1217/1221 nt) sbmA predicted transporter
?REL606 = 3726074 57 (0.670)coding (49/1545 nt) yibO phosphoglyceromutase
* ? REL606 370831 =66 (0.640)3 (0.050) 3/28 NT 8.4% intergenic (+23/‑96) phoA/psiF bacterial alkaline phosphatase/hypothetical protein
?REL606 4533970 = 27 (0.450)coding (156/1461 nt) uxuB D‑mannonate oxidoreductase, NAD‑binding
* ? REL606 = 38998364 (0.620)8 (0.100) 5/36 NT 10.3% coding (575/1374 nt) proY predicted cryptic proline transporter
?REL606 = 3813056 92 (1.190)intergenic (‑137/‑797) ivbL/emrD ilvB operon leader peptide/multidrug efflux system protein
* ? REL606 411751 =19 (0.180)8 (0.080) 3/44 NT 12.3% coding (313/591 nt) thiJ hypothetical protein
?REL606 = 1138232 97 (1.030)coding (395/648 nt) grxB glutaredoxin 2 (Grx2)
* ? REL606 413197 =80 (0.780)16 (0.210) 3/36 NT 19.4% coding (93/492 nt) yajQ nucleotide‑binding protein
?REL606 3219746 = 73 (0.950)coding (344/477 nt) agaB N‑acetylgalactosamine‑specific enzyme IIB component of PTS
* ? REL606 422127 =69 (0.670)8 (0.120) 4/32 NT 15.8% coding (187/948 nt) cyoA cytochrome o ubiquinol oxidase subunit II
?REL606 4480474 = 39 (0.570)coding (497/1191 nt) intB predicted integrase
* ? REL606 422590 =83 (0.810)4 (0.040) 4/46 NT 6.1% intergenic (‑277/+185) cyoA/ampG cytochrome o ubiquinol oxidase subunit II/muropeptide transporter
?REL606 801538 = 45 (0.440)coding (346/1290 nt) bioA adenosylmethionine‑8‑amino‑7‑oxononanoate transaminase
* ? REL606 422591 =80 (0.780)12 (0.150) 3/38 NT 17.9% intergenic (‑278/+184) cyoA/ampG cytochrome o ubiquinol oxidase subunit II/muropeptide transporter
?REL606 = 2605528 47 (0.580)coding (679/1254 nt) glyA serine hydroxymethyltransferase
* ? REL606 422591 =80 (0.780)9 (0.110) 4/38 NT 16.0% intergenic (‑278/+184) cyoA/ampG cytochrome o ubiquinol oxidase subunit II/muropeptide transporter
?REL606 3002837 = 31 (0.380)coding (307/2517 nt) yeeR predicted membrane protein
* ? REL606 422594 =77 (0.750)21 (0.230) 4/42 NT 25.6% intergenic (‑281/+181) cyoA/ampG cytochrome o ubiquinol oxidase subunit II/muropeptide transporter
?REL606 2573117 = 55 (0.610)intergenic (‑11/‑196) yfhM/sseA hypothetical protein/3‑mercaptopyruvate sulfurtransferase
* ? REL606 422594 =77 (0.750)21 (0.220) 7/44 NT 23.0% intergenic (‑281/+181) cyoA/ampG cytochrome o ubiquinol oxidase subunit II/muropeptide transporter
?REL606 = 3721305 76 (0.740)coding (669/1191 nt) lldD L‑lactate dehydrogenase, FMN‑linked
* ? REL606 445976 =79 (0.770)9 (0.120) 4/36 NT 13.8% coding (944/1287 nt) amtB ammonium transporter
?REL606 3083447 = 53 (0.690)coding (197/495 nt) yqhA hypothetical protein
* ? REL606 447249 =84 (0.820)18 (0.180) 5/46 NT 17.5% intergenic (‑21/‑197) tesB/ybaY acyl‑CoA thioesterase II/predicted outer membrane lipoprotein
?REL606 1286712 = 89 (0.900)intergenic (+36/‑147) narI/ECB_01206 nitrate reductase 1, gamma (cytochrome b(NR)) subunit/hypothetical protein
* ? REL606 449635 =24 (0.230)5 (0.070) 3/34 NT 11.1% coding (1050/1551 nt) ylaB conserved inner membrane protein
?REL606 = 3144237 63 (0.870)coding (314/1746 nt) dnaG DNA primase
* ? REL606 456653 =60 (0.580)11 (0.140) 4/36 NT 17.7% coding (1034/1194 nt) acrA multidrug efflux system
?REL606 3845122 = 57 (0.740)coding (269/360 nt) rnpA ribonuclease P
* ? REL606 462517 =55 (0.540)11 (0.120) 4/42 NT 17.3% coding (363/528 nt) priC primosomal replication protein N''
?REL606 1306336 = 57 (0.630)intergenic (‑97/+274) cls/kch cardiolipin synthetase/voltage‑gated potassium channel
* ? REL606 469267 =124 (1.210)5 (0.060) 3/42 NT 4.9% coding (26/645 nt) adk adenylate kinase
?REL606 2766488 = 87 (0.970)coding (154/480 nt) ispF 2‑C‑methyl‑D‑erythritol 2,4‑cyclodiphosphate synthase
* ? REL606 471760 =64 (0.620)13 (0.140) 5/42 NT 15.0% coding (281/960 nt) aes acetyl esterase
?REL606 3912266 = 91 (1.010)intergenic (+46/‑94) ilvL/ilvG ilvG operon leader peptide/acetolactate synthase II, valine insensitive, large subunit
* ? REL606 = 47390487 (0.850)42 (0.540) 6/36 NT 41.1% coding (1402/1677 nt) ybaL predicted transporter with NAD(P)‑binding Rossmann‑fold domain
?REL606 = 1923465 55 (0.710)coding (662/1011 nt) ruvB Holliday junction DNA helicase B
* ? REL606 481061 =70 (0.680)12 (0.160) 4/34 NT 13.9% coding (2487/2505 nt) copA copper transporter
?REL606 = 606452 99 (1.360)coding (767/957 nt) fepB iron‑enterobactin transporter subunit
* ? REL606 489053 =105 (1.020)9 (0.100) 5/42 NT 12.3% coding (303/780 nt) ybbM predicted inner membrane protein
?REL606 3821518 = 37 (0.410)coding (910/1323 nt) glvG predicted 6‑phospho‑beta‑glucosidase
* ? REL606 505984 =28 (0.270)12 (0.130) 6/42 NT 16.8% coding (808/816 nt) allR DNA‑binding transcriptional repressor
?REL606 2525727 = 94 (1.050)coding (4/1350 nt) hyfD hydrogenase 4 membrane subunit
* ? REL606 506020 =104 (1.010)12 (0.120) 4/48 NT 14.8% intergenic (+28/‑62) allR/gcl DNA‑binding transcriptional repressor/glyoxylate carboligase
?REL606 758029 = 34 (0.330)coding (806/1266 nt) tolA cell envelope integrity inner membrane protein TolA
* ? REL606 514780 =90 (0.880)3 (0.050) 3/28 NT 8.3% coding (727/1146 nt) glxK glycerate kinase II
?REL606 1871739 = 14 (0.230)coding (75/1911 nt) yoaA conserved protein with nucleoside triphosphate hydrolase domain
* ? REL606 519489 =96 (0.930)12 (0.160) 3/36 NT 16.6% coding (644/1668 nt) fdrA membrane protein FdrA
?REL606 1815514 = 49 (0.640)coding (1030/1491 nt) ynjC fused transporter subunits of ABC superfamily: membrane components
* ? REL606 = 547699NA (NA)48 (0.470) 30/48 NT NA noncoding (1/768 nt) IS1 repeat region
?REL606 557127 = NA (NA)coding (70/282 nt) ECB_00514 conserved hypothetical protein
* ? REL606 558248 =18 (0.180)6 (0.090) 4/32 NT 19.7% coding (185/294 nt) ECB_00516 conserved hypothetical protein
?REL606 3001100 = 37 (0.540)coding (1537/2847 nt) flu antigen 43 (Ag43) phase‑variable biofilm formation autotransporter
* ? REL606 564054 =42 (0.410)9 (0.120) 3/34 NT 14.5% coding (2252/2973 nt) nfrA bacteriophage N4 receptor, outer membrane subunit
?REL606 1414711 = 76 (1.040)coding (223/276 nt) racC predicted protein
* ? REL606 575058 =51 (0.500)11 (0.140) 3/38 NT 9.8% coding (616/1449 nt) cusS sensory histidine kinase in two‑component regulatory system with CusR, senses copper ions
?REL606 = 2762587 162 (1.990)coding (1028/1140 nt) nlpD predicted outer membrane lipoprotein
* ? REL606 580467 =60 (0.580)4 (0.050) 3/36 NT 9.1% coding (851/3144 nt) cusA copper/silver efflux system, membrane component
?REL606 2397842 = 35 (0.450)coding (824/2646 nt) yfcTU predicted outer membrane export usher protein
* ? REL606 580468 =60 (0.580)16 (0.200) 4/38 NT 16.7% coding (852/3144 nt) cusA copper/silver efflux system, membrane component
?REL606 2715365 = 112 (1.380)coding (1506/2631 nt) alaS alanyl‑tRNA synthetase
* ? REL606 581288 =99 (0.960)12 (0.150) 3/38 NT 17.1% coding (1672/3144 nt) cusA copper/silver efflux system, membrane component
?REL606 1956195 = 38 (0.470)coding (420/579 nt) flhC DNA‑binding transcriptional dual regulator with FlhD
* ? REL606 = 58340744 (0.430)12 (0.160) 3/34 NT 15.9% coding (546/1377 nt) pheP phenylalanine transporter
?REL606 3882315 = 96 (1.320)coding (103/816 nt) atpB F0F1 ATP synthase subunit A
* ? REL606 588495 =NA (NA)5 (0.050) 4/44 NT NA noncoding (1/1977 nt) IS150 repeat region
?REL606 589936 = NA (NA)noncoding (387/768 nt) IS1 repeat region
* ? REL606 594300 =32 (0.310)8 (0.110) 5/34 NT 13.7% coding (902/2241 nt) fepA iron‑enterobactin outer membrane transporter
?REL606 = 3534924 78 (1.070)coding (8/1497 nt) ftsY fused Signal Recognition Particle (SRP) receptor: membrane binding protein/conserved protein
* ? REL606 601491 =81 (0.790)7 (0.100) 3/34 NT 10.1% coding (530/1134 nt) fepE regulator of length of O‑antigen component of lipopolysaccharide chains
?REL606 2785963 = 67 (0.920)coding (408/1338 nt) ygcS predicted transporter
* ? REL606 610886 =57 (0.550)19 (0.260) 4/34 NT 28.5% coding (485/858 nt) entB isochorismatase
?REL606 1306336 = 55 (0.760)intergenic (‑97/+274) cls/kch cardiolipin synthetase/voltage‑gated potassium channel
* ? REL606 = 61503553 (0.520)4 (0.050) 3/38 NT 7.4% coding (157/198 nt) ybdD hypothetical protein
?REL606 = 3625455 58 (0.710)pseudogene (8/738 nt) yhjQ b3534; cell division protein (chromosome partitioning ATPase)
* ? REL606 640115 =106 (1.030)28 (0.380) 5/34 NT 24.6% intergenic (+33/+22) cspE/ccrB cold shock protein E/camphor resistance protein CrcB
?REL606 2746531 = 97 (1.330)coding (671/873 nt) hypB GTP hydrolase involved in nickel liganding into hydrogenases
* ? REL606 640120 =107 (1.040)10 (0.100) 3/46 NT 11.1% intergenic (+38/+17) cspE/ccrB cold shock protein E/camphor resistance protein CrcB
?REL606 2388696 = 58 (0.590)coding (457/810 nt) yfcA conserved inner membrane protein
* ? REL606 = 64299484 (0.820)9 (0.110) 4/38 NT 12.4% intergenic (‑195/+14) lipA/ybeF lipoyl synthase/predicted DNA‑binding transcriptional regulator
?REL606 967183 = 61 (0.750)coding (423/591 nt) ycaK hypothetical protein
* ? REL606 = 65726081 (0.790)7 (0.090) 5/38 NT 8.3% coding (108/2583 nt) leuS leucyl‑tRNA synthetase
?REL606 = 1387545 90 (1.110)coding (247/966 nt) ycjG L‑Ala‑D/L‑Glu epimerase
* ? REL606 = 66468767 (0.650)34 (0.380) 20/42 NT 39.4% intergenic (‑78/‑48) gltL/insJ‑2 ATP‑binding protein of glutamate/aspartate transport system; b0652_1/IS150 hypothetical protein
?REL606 666134 = 46 (0.510)pseudogene (354/387 nt) gltL ATP‑binding protein of glutamate/aspartate transport system; b0652_2
* ? REL606 664688 =NA (NA)108 (1.150) 38/44 NT 100% noncoding (1/1443 nt) IS150 repeat region
?REL606 1270660 = 0 (0.000)intergenic (‑167/+238) ldrC/chaA toxic polypeptide, small/calcium/sodium:proton antiporter
* ? REL606 = 67279679 (0.770)10 (0.150) 3/32 NT 16.4% coding (181/1539 nt) lnt apolipoprotein N‑acyltransferase
?REL606 1048881 = 49 (0.720)intergenic (‑78/‑349) serT/hyaA tRNA‑Ser/hydrogenase 1, small subunit
* ? REL606 = 67940175 (0.730)6 (0.070) 3/38 NT 13.9% intergenic (‑174/+207) metT/asnB tRNA‑Met/asparagine synthetase B
?REL606 4198479 = 15 (0.180)coding (341/1737 nt) aceK bifunctional isocitrate dehydrogenase kinase/phosphatase protein
* ? REL606 = 68136568 (0.660)10 (0.180) 3/26 NT 18.0% intergenic (‑93/+304) asnB/nagD asparagine synthetase B/UMP phosphatase
?REL606 = 2930921 54 (0.970)coding (734/744 nt) ygfF predicted NAD(P)‑binding oxidoreductase with NAD(P)‑binding Rossmann‑fold domain
* ? REL606 = 68792162 (0.600)12 (0.130) 4/44 NT 12.4% coding (1883/1947 nt) nagE fused N‑acetyl glucosamine specific PTS enzyme: IIC, IIB , and IIA components
?REL606 970674 = 112 (1.190)intergenic (‑27/+28) pflB/focA pyruvate formate lyase I/formate transporter
* ? REL606 = 699047102 (0.990)3 (0.040) 3/36 NT 4.6% coding (1314/1320 nt) potE putrescine/proton symporter: putrescine/ornithine antiporter
?REL606 1115826 = 48 (0.620)coding (428/834 nt) csgG outer membrane lipoprotein
* ? REL606 734239 =59 (0.570)18 (0.180) 6/48 NT 29.0% coding (1021/1284 nt) gltA citrate synthase
?REL606 1556579 = 29 (0.280)intergenic (‑104/+298) ydeN/ydeO hypothetical protein/predicted DNA‑binding transcriptional acfivator
* ? REL606 = 73827923 (0.220)14 (0.230) 3/28 NT 31.3% coding (1582/1767 nt) sdhA succinate dehydrogenase flavoprotein subunit
?REL606 = 3686151 48 (0.800)coding (411/741 nt) yiaT hypothetical protein
* ? REL606 741667 =102 (0.990)24 (0.310) 5/36 NT 25.9% coding (2171/2802 nt) sucA alpha‑ketoglutarate decarboxylase
?REL606 = 1476120 81 (0.790)coding (71/1176 nt) ydcO predicted benzoate transporter
* ? REL606 = 75650964 (0.620)16 (0.210) 4/36 NT 23.0% coding (475/693 nt) tolQ membrane spanning protein in TolA‑TolQ‑TolR complex
?REL606 1539626 = 59 (0.770)coding (46/2400 nt) dos cAMP phosphodiesterase, heme‑regulated
* ? REL606 790656 =71 (0.690)5 (0.070) 3/34 NT 9.7% coding (88/186 nt) ECB_00731 conserved hypothetical protein
?REL606 1598222 = 43 (0.590)coding (459/1461 nt) ydfI predicted mannonate dehydrogenase
* ? REL606 805852 =114 (1.110)112 (1.380) 8/38 NT 55.4% intergenic (+279/‑300) bioD/uvrB dethiobiotin synthetase/excinuclease ABC subunit B
?REL606 = 1193676 NA (NA)noncoding (62/768 nt) IS1 repeat region
* ? REL606 = 842815109 (1.060)4 (0.040) 3/44 NT 4.8% intergenic (‑93/‑260) ybiF/ompX threonine and homoserine efflux system/outer membrane protein X
?REL606 3607355 = 58 (0.620)coding (503/2076 nt) yhjG predicted outer membrane biogenesis protein
* ? REL606 866988 =115 (1.120)7 (0.090) 4/38 NT 9.9% coding (1206/2097 nt) yliE conserved inner membrane protein
?REL606 = 4527146 37 (0.450)coding (1137/2637 nt) fimD outer membrane usher protein, type 1 fimbrial synthesis
* ? REL606 875814 =63 (0.610)19 (0.220) 5/40 NT 23.4% coding (127/597 nt) ybjG undecaprenyl pyrophosphate phosphatase
?REL606 = 3285418 72 (0.840)coding (277/654 nt) yhbL isoprenoid biosynthesis protein with amidotransferase‑like domain
* ? REL606 894104 =69 (0.670)17 (0.200) 5/40 NT 21.9% coding (646/1767 nt) ECB_00833 Terminase, ATPase subunit
?REL606 = 2195255 64 (0.750)coding (108/837 nt) yeiG predicted esterase
* ? REL606 923960 =74 (0.720)7 (0.090) 3/36 NT 8.9% coding (1030/1431 nt) ybjT conserved protein with NAD(P)‑binding Rossmann‑fold domain
?REL606 3472589 = 88 (1.140)coding (758/879 nt) yhgA predicted transposase
* ? REL606 924268 =101 (0.980)11 (0.140) 3/36 NT 16.3% coding (722/1431 nt) ybjT conserved protein with NAD(P)‑binding Rossmann‑fold domain
?REL606 2554226 = 37 (0.480)coding (664/1467 nt) guaB inositol‑5‑monophosphate dehydrogenase
* ? REL606 924268 =101 (0.980)7 (0.090) 3/36 NT 13.1% coding (722/1431 nt) ybjT conserved protein with NAD(P)‑binding Rossmann‑fold domain
?REL606 = 3633290 17 (0.220)coding (37/1005 nt) dppF dipeptide transporter
* ? REL606 924268 =101 (0.980)9 (0.120) 3/36 NT 13.4% coding (722/1431 nt) ybjT conserved protein with NAD(P)‑binding Rossmann‑fold domain
?REL606 = 4366448 41 (0.530)coding (1078/3324 nt) yjeP predicted mechanosensitive channel
* ? REL606 924276 =93 (0.910)10 (0.100) 3/46 NT 12.3% coding (714/1431 nt) ybjT conserved protein with NAD(P)‑binding Rossmann‑fold domain
?REL606 = 1365457 53 (0.540)coding (824/978 nt) pspF DNA‑binding transcriptional activator
* ? REL606 929308 =57 (0.550)8 (0.120) 3/32 NT 13.8% coding (1214/1653 nt) hcp hydroxylamine reductase
?REL606 = 3040633 62 (0.910)coding (654/810 nt) pppA bifunctional prepilin leader peptidase/ methylase
* ? REL606 932696 =61 (0.590)12 (0.180) 3/32 NT 18.9% coding (59/696 nt) aqpZ aquaporin Z
?REL606 = 3040633 62 (0.910)coding (654/810 nt) pppA bifunctional prepilin leader peptidase/ methylase
* ? REL606 947579 =44 (0.430)9 (0.090) 4/46 NT 13.7% coding (442/1767 nt) cydD fused cysteine transporter subunits of ABC superfamily: membrane component/ATP‑binding component
?REL606 = 3484563 71 (0.720)coding (887/1017 nt) rtcA RNA 3'‑terminal‑phosphate cyclase
* ? REL606 954088 =106 (1.030)4 (0.040) 3/48 NT 4.2% coding (3807/4029 nt) ftsK DNA‑binding membrane protein required for chromosome resolution and partitioning
?REL606 4604384 = 76 (0.740)coding (394/864 nt) yjjW predicted pyruvate formate lyase activating enzyme
* ? REL606 957480 =61 (0.590)11 (0.150) 3/34 NT 20.1% coding (960/1293 nt) serS seryl‑tRNA synthetase
?REL606 = 3467034 44 (0.600)coding (963/2319 nt) yhgF predicted transcriptional accessory protein
* ? REL606 965820 =63 (0.610)8 (0.100) 3/36 NT 12.3% coding (842/909 nt) ycaN predicted DNA‑binding transcriptional regulator
?REL606 4368357 = 67 (0.870)coding (159/969 nt) psd phosphatidylserine decarboxylase
* ? REL606 = 98960956 (0.540)13 (0.160) 4/38 NT 32.0% coding (766/894 nt) ycbJ hypothetical protein
?REL606 2795469 = 11 (0.140)coding (831/873 nt) ygcG hypothetical protein
* ? REL606 1004939 =65 (0.630)15 (0.180) 5/40 NT 19.2% coding (1138/1401 nt) asnS asparaginyl‑tRNA synthetase
?REL606 1339539 = 72 (0.840)coding (610/1170 nt) yciM hypothetical protein
* ? REL606 = 1006225100 (0.970)9 (0.110) 3/38 NT 13.2% intergenic (‑149/+20) asnS/pncB asparaginyl‑tRNA synthetase/nicotinate phosphoribosyltransferase
?REL606 = 4210740 39 (0.480)intergenic (‑178/+75) yjbD/lysC hypothetical protein/aspartate kinase III
* ? REL606 = 101794468 (0.660)11 (0.110) 7/48 NT 11.4% coding (1638/2601 nt) ycbS predicted outer membrane usher protein
?REL606 = 3424887 103 (1.000)intergenic (+105/‑21) nirD/nirC nitrite reductase small subunit/nitrite transporter
* ? REL606 1036060 =100 (0.970)19 (0.190) 7/46 NT 20.0% intergenic (+32/+44) ycbG/ompA hypothetical protein/outer membrane protein A (3a;II*;G;d)
?REL606 3483139 = 59 (0.570)coding (1455/2706 nt) malT transcriptional regulator MalT
* ? REL606 = 1036071104 (1.010)18 (0.180) 6/46 NT 17.6% intergenic (+43/+33) ycbG/ompA hypothetical protein/outer membrane protein A (3a;II*;G;d)
?REL606 = 2316746 69 (0.700)coding (216/891 nt) yfbH hypothetical protein
* ? REL606 = 1036071104 (1.010)13 (0.130) 7/46 NT 13.9% intergenic (+43/+33) ycbG/ompA hypothetical protein/outer membrane protein A (3a;II*;G;d)
?REL606 3487307 = 61 (0.620)coding (440/1599 nt) rtcR sigma 54‑dependent transcriptional regulator of rtcBA expression
* ? REL606 1050924 =43 (0.420)6 (0.070) 4/40 NT 9.8% coding (580/1794 nt) hyaB hydrogenase 1, large subunit
?REL606 1543472 = 75 (0.880)coding (969/1536 nt) xasA predicted glutamate:gamma‑aminobutyric acid antiporter
* ? REL606 = 105493386 (0.840)11 (0.120) 4/44 NT 9.8% coding (103/1545 nt) appC cytochrome bd‑II oxidase, subunit I
?REL606 = 3766502 123 (1.310)coding (1206/1206 nt) gltS glutamate transporter
* ? REL606 = 107214974 (0.720)4 (0.040) 3/42 NT 4.8% coding (320/2745 nt) torS hybrid sensory histidine kinase in two‑component regulatory system with TorR
?REL606 3712714 = 106 (1.030)coding (451/684 nt) ECB_03459 conserved hypothetical protein
* ? REL606 = 107576568 (0.660)14 (0.170) 4/38 NT 15.8% coding (220/2547 nt) torA trimethylamine N‑oxide (TMAO) reductase I, catalytic subunit
?REL606 = 3523984 95 (1.170)coding (128/714 nt) livF leucine/isoleucine/valine transporter subunit
* ? REL606 = 1076256103 (1.000)12 (0.160) 3/36 NT 15.1% coding (711/2547 nt) torA trimethylamine N‑oxide (TMAO) reductase I, catalytic subunit
?REL606 3800450 = 58 (0.750)intergenic (+10/+31) ECB_03545/yicM hypothetical protein/predicted transporter
* ? REL606 1076727 =60 (0.580)8 (0.090) 5/40 NT 14.4% coding (1182/2547 nt) torA trimethylamine N‑oxide (TMAO) reductase I, catalytic subunit
?REL606 3786648 = 45 (0.530)coding (75/339 nt) ECB_03525 conserved hypothetical protein
* ? REL606 1087708 =57 (0.550)7 (0.090) 3/36 NT 11.8% coding (342/801 nt) ycdJ predicted hydrolase
?REL606 = 1145443 62 (0.800)intergenic (‑8/‑147) flgA/flgB flagellar basal body P‑ring biosynthesis protein A/flagellar basal‑body rod protein B
* ? REL606 1095862 =53 (0.520)3 (0.050) 3/28 NT 10.4% coding (274/1509 nt) putP proline:sodium symporter
?REL606 1585457 = 21 (0.350)coding (495/666 nt) marC predicted transporter
* ? REL606 1112140 =NA (NA)14 (0.140) 5/48 NT 35.9% noncoding (81/88 nt) serX tRNA‑Ser
?REL606 = 3173882 25 (0.240)coding (905/1245 nt) ygjU sodium:serine/threonine symporter
* ? REL606 1133033 =122 (1.190)8 (0.100) 3/38 NT 9.4% coding (13/576 nt) yceI hypothetical protein
?REL606 = 2612120 57 (0.700)intergenic (‑323/+253) yfhK/purL predicted sensory kinase in two‑component system/phosphoribosylformylglycinamidine synthase
* ? REL606 = 1145450100 (0.970)8 (0.100) 4/36 NT 10.0% intergenic (‑15/‑140) flgA/flgB flagellar basal body P‑ring biosynthesis protein A/flagellar basal‑body rod protein B
?REL606 = 3613817 69 (0.900)coding (1255/1950 nt) yhjK predicted diguanylate cyclase
* ? REL606 1157306 =35 (0.340)4 (0.050) 4/38 NT 11.3% coding (1631/3186 nt) rne fused ribonucleaseE: endoribonuclease/RNA‑binding protein/RNA degradosome binding protein
?REL606 = 1452435 35 (0.430)intergenic (‑244/‑14) acpD/hrpA acyl carrier protein phosphodiesterase/ATP‑dependent helicase
* ? REL606 = 118158088 (0.860)8 (0.100) 3/38 NT 11.2% coding (919/1305 nt) ndh respiratory NADH dehydrogenase 2/cupric reductase
?REL606 2872317 = 57 (0.700)coding (1204/1263 nt) lysA diaminopimelate decarboxylase, PLP‑binding
* ? REL606 = 1183967102 (0.990)18 (0.180) 7/48 NT 19.3% intergenic (+43/+40) ycfR/ycfS hypothetical protein/hypothetical protein
?REL606 = 3012564 49 (0.480)coding (248/1020 nt) ECB_02814 conserved hypothetical protein
* ? REL606 = 1183967102 (0.990)15 (0.150) 4/46 NT 15.2% intergenic (+43/+40) ycfR/ycfS hypothetical protein/hypothetical protein
?REL606 = 4549416 69 (0.700)coding (18/1233 nt) yjiO multidrug efflux system protein
* ? REL606 1199795 =69 (0.670)4 (0.060) 3/30 NT 7.4% coding (20/828 nt) potB spermidine/putrescine ABC transporter membrane protein
?REL606 = 3283512 57 (0.890)intergenic (+39/‑175) ptsO/yrbL phosphohistidinoprotein‑hexose phosphotransferase component of N‑regulated PTS system (Npr)/hypothetical protein
* ? REL606 1204666 =70 (0.680)9 (0.120) 4/36 NT 11.7% coding (481/1461 nt) phoQ sensory histidine kinase in two‑compoent regulatory system with PhoP
?REL606 3975303 = 83 (1.080)coding (677/801 nt) yigL predicted hydrolase
* ? REL606 = 121335336 (0.350)4 (0.060) 3/30 NT 9.5% intergenic (‑85/+136) ycgX/ycgE hypothetical protein/predicted DNA‑binding transcriptional regulator
?REL606 = 4512602 54 (0.840)coding (720/747 nt) yjhP predicted methyltransferase
* ? REL606 1249678 =70 (0.680)6 (0.090) 4/30 NT 11.3% coding (230/633 nt) dhaL dihydroxyacetone kinase, C‑terminal domain
?REL606 1306336 = 50 (0.780)intergenic (‑97/+274) cls/kch cardiolipin synthetase/voltage‑gated potassium channel
* ? REL606 1255973 =72 (0.700)12 (0.140) 4/40 NT 19.0% coding (130/2868 nt) ycgV predicted adhesin
?REL606 = 3223859 42 (0.490)coding (537/696 nt) yraI predicted periplasmic pilin chaperone
* ? REL606 1286707 =97 (0.940)9 (0.110) 4/38 NT 10.5% intergenic (+31/‑152) narI/ECB_01206 nitrate reductase 1, gamma (cytochrome b(NR)) subunit/hypothetical protein
?REL606 = 1424360 NA (NA)coding (192/294 nt) ECB_01344 conserved hypothetical protein
* ? REL606 1286707 =97 (0.940)17 (0.210) 5/38 NT 21.4% intergenic (+31/‑152) narI/ECB_01206 nitrate reductase 1, gamma (cytochrome b(NR)) subunit/hypothetical protein
?REL606 = 4286236 48 (0.590)coding (386/930 nt) alsK D‑allose kinase
* ? REL606 1286708 =97 (0.940)10 (0.120) 4/40 NT 12.7% intergenic (+32/‑151) narI/ECB_01206 nitrate reductase 1, gamma (cytochrome b(NR)) subunit/hypothetical protein
?REL606 = 4391784 57 (0.670)coding (602/1164 nt) yjfC predicted synthetase/amidase
* ? REL606 1306117 =70 (0.680)13 (0.140) 4/44 NT 14.3% coding (123/1461 nt) cls cardiolipin synthetase
?REL606 4085858 = 92 (0.980)intergenic (+56/‑93) cpxP/fieF periplasmic protein combats stress/ferrous iron efflux protein F
* ? REL606 1306326 =88 (0.860)10 (0.170) 3/28 NT 18.1% intergenic (‑87/+284) cls/kch cardiolipin synthetase/voltage‑gated potassium channel
?REL606 = 2380515 39 (0.650)coding (929/1137 nt) pdxB erythronate‑4‑phosphate dehydrogenase
* ? REL606 1306327 =87 (0.850)9 (0.140) 3/30 NT 15.9% intergenic (‑88/+283) cls/kch cardiolipin synthetase/voltage‑gated potassium channel
?REL606 = 3884923 41 (0.640)coding (1072/1890 nt) gidA glucose‑inhibited division protein A
* ? REL606 1306329 =80 (0.780)14 (0.190) 4/34 NT 22.1% intergenic (‑90/+281) cls/kch cardiolipin synthetase/voltage‑gated potassium channel
?REL606 = 3839377 42 (0.580)coding (1104/2415 nt) gyrB DNA gyrase subunit B
* ? REL606 1332666 =72 (0.700)5 (0.060) 4/36 NT 7.6% coding (440/975 nt) cysB DNA‑binding transcriptional dual regulator, O‑acetyl‑L‑serine‑binding
?REL606 = 4432999 68 (0.880)intergenic (‑97/‑213) ppa/ytfQ inorganic pyrophosphatase/predicted sugar transporter subunit: periplasmic‑binding component of ABC superfamily
* ? REL606 1332936 =97 (0.940)12 (0.150) 5/38 NT 15.3% coding (710/975 nt) cysB DNA‑binding transcriptional dual regulator, O‑acetyl‑L‑serine‑binding
?REL606 = 2871320 56 (0.690)coding (101/1032 nt) galR DNA‑binding transcriptional repressor
* ? REL606 = 133592652 (0.510)11 (0.170) 5/30 NT 18.7% coding (1724/2676 nt) acnA aconitate hydratase
?REL606 = 2863313 63 (0.980)coding (285/531 nt) ygdP dinucleoside polyphosphate hydrolase
* ? REL606 1337070 =141 (1.370)6 (0.070) 5/42 NT 7.6% coding (463/591 nt) ribA GTP cyclohydrolase II protein
?REL606 4326307 = 22 (0.240)coding (1153/1341 nt) dcuB C4‑dicarboxylate antiporter
* ? REL606 1349554 =66 (0.640)10 (0.130) 4/36 NT 18.6% intergenic (‑146/+222) fabI/ycjD enoyl‑(acyl carrier protein) reductase/hypothetical protein
?REL606 = 3574369 38 (0.490)coding (1504/2043 nt) prlC oligopeptidase A
* ? REL606 1349559 =56 (0.540)6 (0.060) 3/46 NT 8.3% intergenic (‑151/+217) fabI/ycjD enoyl‑(acyl carrier protein) reductase/hypothetical protein
?REL606 = 2307173 79 (0.800)coding (767/1218 nt) yfaW predicted enolase
* ? REL606 = 1398219108 (1.050)6 (0.090) 3/32 NT 8.5% coding (725/1527 nt) abgT predicted cryptic aminobenzoyl‑glutamate transporter
?REL606 = 1743481 58 (0.850)coding (2472/3057 nt) ydiJ predicted FAD‑linked oxidoreductase
* ? REL606 1430232 =98 (0.950)7 (0.100) 3/34 NT 10.1% coding (2159/3525 nt) ydbK fused predicted pyruvate‑flavodoxin oxidoreductase: conserved protein/conserved protein/FeS binding protein
?REL606 3284457 = 55 (0.760)coding (588/729 nt) mtgA monofunctional biosynthetic peptidoglycan transglycosylase
* ? REL606 = 146226959 (0.570)9 (0.100) 8/42 NT 14.8% intergenic (‑31/‑310) mokB/trg regulatory peptide/methyl‑accepting chemotaxis protein III, ribose and galactose sensor receptor
?REL606 = 3894996 NA (NA)noncoding (1443/1443 nt) IS150 repeat region
* ? REL606 = 1493185140 (1.360)10 (0.120) 4/38 NT 10.9% intergenic (‑10/‑232) yncD/yncE predicted iron outer membrane transporter/hypothetical protein
?REL606 3269358 = 53 (0.650)coding (415/972 nt) ispB octaprenyl diphosphate synthase
* ? REL606 1493949 =71 (0.690)13 (0.160) 5/38 NT 17.3% coding (533/1062 nt) yncE hypothetical protein
?REL606 = 1619524 68 (0.840)intergenic (‑133/+84) rem/hokD predicted protein/small toxic polypeptide
* ? REL606 1494073 =76 (0.740)15 (0.170) 7/42 NT 16.6% coding (657/1062 nt) yncE hypothetical protein
?REL606 4351442 = 84 (0.930)intergenic (+50/‑88) groEL/yjeI chaperonin GroEL/hypothetical protein
* ? REL606 1495445 =79 (0.770)10 (0.110) 4/44 NT 13.0% coding (648/1500 nt) ansP L‑asparagine transporter
?REL606 3277263 = 61 (0.650)coding (763/987 nt) yrbH D‑arabinose 5‑phosphate isomerase
* ? REL606 1495878 =73 (0.710)13 (0.280) 3/22 NT 21.2% coding (215/1500 nt) ansP L‑asparagine transporter
?REL606 = 1714633 138 (1.340)intergenic (‑76/+90) ydhP/ECB_01628 putative transport protein (MFS family); b1657_2/predicted transporter
* ? REL606 = 149942988 (0.860)12 (0.150) 6/38 NT 14.1% coding (1346/2127 nt) ECB_01413 conserved hypothetical protein
?REL606 1692278 = 76 (0.930)coding (806/864 nt) pdxY pyridoxine kinase
* ? REL606 1500892 =NA (NA)5 (0.060) 3/36 NT 12.2% coding (616/4224 nt) rhsE rhsE element core protein RshE
?REL606 = 1977657 48 (0.470)coding (181/1005 nt) yedY hypothetical protein
* ? REL606 1510513 =81 (0.790)16 (0.210) 4/36 NT 22.7% coding (256/681 nt) narV nitrate reductase 2 (NRZ), gamma subunit
?REL606 4138913 = 48 (0.620)coding (563/918 nt) oxyR DNA‑binding transcriptional dual regulator
* ? REL606 1534318 =71 (0.690)12 (0.150) 4/38 NT 24.9% coding (550/1023 nt) yddR D‑ala‑D‑ala transporter subunit
?REL606 = 2036370 16 (0.200)coding (589/1113 nt) wbbC putative glycosyltransferase WbbC
* ? REL606 1539621 =78 (0.760)8 (0.100) 4/38 NT 13.6% coding (51/2400 nt) dos cAMP phosphodiesterase, heme‑regulated
?REL606 = 3363882 40 (0.490)coding (771/1290 nt) rrmB 16S rRNA m5C967 methyltransferase, S‑adenosyl‑L‑methionine‑dependent
* ? REL606 1539621 =78 (0.760)11 (0.140) 5/38 NT 16.2% coding (51/2400 nt) dos cAMP phosphodiesterase, heme‑regulated
?REL606 3527786 = 52 (0.640)coding (449/1110 nt) livK leucine transporter subunit
* ? REL606 1539621 =78 (0.760)10 (0.120) 3/38 NT 16.0% coding (51/2400 nt) dos cAMP phosphodiesterase, heme‑regulated
?REL606 = 4445223 43 (0.530)coding (715/2139 nt) nrdD anaerobic ribonucleoside triphosphate reductase
* ? REL606 1544434 =52 (0.510)6 (0.060) 4/46 NT 10.0% coding (7/1536 nt) xasA predicted glutamate:gamma‑aminobutyric acid antiporter
?REL606 = 2047872 58 (0.590)coding (1256/1395 nt) wcaM predicted colanic acid biosynthesis protein
* ? REL606 1587129 =65 (0.630)7 (0.090) 3/36 NT 12.3% coding (244/435 nt) marR DNA‑binding transcriptional repressor of multiple antibiotic resistance
?REL606 2696580 = 51 (0.660)coding (481/2145 nt) nrdE ribonucleotide‑diphosphate reductase alpha subunit
* ? REL606 1590579 =43 (0.420)11 (0.140) 3/38 NT 20.2% intergenic (+294/+147) ydeE/ydeH predicted transporter/hypothetical protein
?REL606 = 3487475 53 (0.650)coding (608/1599 nt) rtcR sigma 54‑dependent transcriptional regulator of rtcBA expression
* ? REL606 = 159309734 (0.330)11 (0.130) 6/40 NT 16.5% intergenic (+40/+4) ydeJ/dcp competence damage‑inducible protein A/dipeptidyl carboxypeptidase II
?REL606 4085859 = 83 (0.970)intergenic (+57/‑92) cpxP/fieF periplasmic protein combats stress/ferrous iron efflux protein F
* ? REL606 = 159874160 (0.580)10 (0.100) 3/46 NT 15.9% intergenic (‑61/+28) ydfI/ydfJ predicted mannonate dehydrogenase/predicted transporter
?REL606 = 3347592 48 (0.490)coding (552/918 nt) yhdW predicted amino‑acid transporter subunit
* ? REL606 1609469 =55 (0.540)5 (0.060) 3/42 NT 9.8% coding (36/207 nt) ybcW predicted protein
?REL606 2545121 = 44 (0.490)coding (1259/2067 nt) ppk polyphosphate kinase
* ? REL606 1661078 =57 (0.550)10 (0.120) 4/40 NT 15.8% coding (1002/1302 nt) rstB sensory histidine kinase in two‑component regulatory system with RstA
?REL606 = 3625456 59 (0.690)pseudogene (7/738 nt) yhjQ b3534; cell division protein (chromosome partitioning ATPase)
* ? REL606 = 167341370 (0.680)24 (0.250) 7/44 NT 28.7% intergenic (‑147/+244) uidA/uidR beta‑D‑glucuronidase/DNA‑binding transcriptional repressor
?REL606 = 4601575 55 (0.580)intergenic (+52/‑70) ytjA/yjjU hypothetical protein/predicted esterase
* ? REL606 = 168661182 (0.800)5 (0.050) 3/48 NT 10.1% coding (276/1059 nt) rnfD electron transport complex protein RnfD
?REL606 1736972 = 7 (0.070)coding (819/1221 nt) sufS selenocysteine lyase
* ? REL606 = 168661182 (0.800)12 (0.120) 3/48 NT 15.0% coding (276/1059 nt) rnfD electron transport complex protein RnfD
?REL606 = 4059472 54 (0.530)coding (536/636 nt) fdoI formate dehydrogenase‑O, cytochrome b556 subunit
* ? REL606 1689078 =46 (0.450)9 (0.120) 4/34 NT 15.7% coding (362/636 nt) nth DNA glycosylase and apyrimidinic (AP) lyase (endonuclease III)
?REL606 = 1996353 64 (0.880)coding (1494/1644 nt) yeeO predicted multidrug efflux system
* ? REL606 1691508 =100 (0.970)7 (0.100) 3/34 NT 8.7% intergenic (+43/‑63) ydgR/gst putative tripeptide transporter permease/glutathionine S‑transferase
?REL606 = 1806767 76 (1.040)coding (233/1479 nt) astD succinylglutamic semialdehyde dehydrogenase
* ? REL606 1711816 =78 (0.760)21 (0.250) 4/40 NT 22.6% coding (188/816 nt) ydhO predicted lipoprotein
?REL606 = 2450890 79 (0.920)intergenic (‑182/+27) yfeA/alaX predicted diguanylate cyclase/tRNA‑Ala
* ? REL606 1723584 =50 (0.490)4 (0.050) 3/36 NT 6.2% intergenic (‑190/‑118) ydhQ/valV hypothetical protein/tRNA‑Val
?REL606 = 2780594 110 (1.070)intergenic (‑196/‑120) cysJ/ygcM sulfite reductase, alpha subunit, flavoprotein/6‑pyruvoyl tetrahydrobiopterin synthase (PTPS)
* ? REL606 1731442 =72 (0.700)7 (0.070) 3/46 NT 11.5% coding (303/627 nt) ydhY predicted 4Fe‑4S ferridoxin‑type protein
?REL606 3480446 = 39 (0.400)coding (628/2394 nt) malP maltodextrin phosphorylase
* ? REL606 1760819 =58 (0.560)7 (0.080) 5/42 NT 9.0% coding (575/1701 nt) ydiD hypothetical protein
?REL606 = 4434365 91 (1.010)coding (58/1503 nt) ytfR predicted sugar transporter subunit: ATP‑binding component of ABC superfamily
* ? REL606 = 177442943 (0.420)8 (0.090) 4/40 NT 14.3% coding (783/2388 nt) pheT phenylalanyl‑tRNA synthetase beta subunit
?REL606 = 2595910 60 (0.700)coding (551/1062 nt) yphC predicted oxidoreductase, Zn‑dependent and NAD(P)‑binding
* ? REL606 1822767 =84 (0.820)11 (0.140) 3/38 NT 13.7% coding (1422/1962 nt) topB DNA topoisomerase III
?REL606 = 2900727 72 (0.890)coding (86/771 nt) yqeC hypothetical protein
* ? REL606 1830987 =34 (0.330)6 (0.080) 4/36 NT 13.9% coding (221/1359 nt) ydjE predicted transporter
?REL606 = 1996585 49 (0.640)coding (1262/1644 nt) yeeO predicted multidrug efflux system
* ? REL606 1857572 =NA (NA)13 (0.200) 4/30 NT 17.7% noncoding (509/1343 nt) IS186 repeat region
?REL606 = 2118058 97 (0.940)coding (720/2292 nt) ECB_02004 Replication gene A protein
* ? REL606 = 185846047 (0.460)4 (0.050) 4/40 NT 6.2% intergenic (+227/+239) insL‑4/yeaS putative transposase insL for insertion sequence IS186/neutral amino‑acid efflux system
?REL606 = 4005717 82 (0.960)intergenic (+18/+265) fre/fadA NAD(P)H‑flavin reductase/acetyl‑CoA acetyltransferase
* ? REL606 = 188990587 (0.850)12 (0.130) 5/42 NT 17.4% coding (1053/1374 nt) yebQ predicted transporter
?REL606 2379272 = 38 (0.420)coding (970/1014 nt) usg hypothetical protein
* ? REL606 1922884 =47 (0.460)13 (0.150) 5/40 NT 20.9% intergenic (+109/+232) znuB/ruvB high‑affinity zinc transporter membrane component/Holliday junction DNA helicase B
?REL606 = 3625456 59 (0.690)pseudogene (7/738 nt) yhjQ b3534; cell division protein (chromosome partitioning ATPase)
* ? REL606 1924695 =91 (0.890)6 (0.100) 3/28 NT 9.9% coding (52/612 nt) ruvA Holliday junction DNA helicase motor protein
?REL606 = 2696376 56 (0.930)coding (277/2145 nt) nrdE ribonucleotide‑diphosphate reductase alpha subunit
* ? REL606 1924962 =56 (0.540)10 (0.100) 4/48 NT 12.3% intergenic (‑216/‑59) ruvA/yebB Holliday junction DNA helicase motor protein/hypothetical protein
?REL606 = 2078183 86 (0.840)coding (1712/3306 nt) yegE predicted diguanylate cyclase, GGDEF domain signalling protein
* ? REL606 1947885 =81 (0.790)20 (0.200) 9/46 NT 16.6% coding (250/861 nt) cheR chemotaxis regulator, protein‑glutamate methyltransferase
?REL606 = 3428485 123 (1.250)coding (671/1338 nt) yhfM predicted fructoselysine transporter
* ? REL606 = 197907688 (0.860)10 (0.110) 4/44 NT 14.7% coding (595/636 nt) yedZ hypothetical protein
?REL606 = 2901067 35 (0.370)coding (153/579 nt) ygfJ hypothetical protein
* ? REL606 2017663 =30 (0.290)18 (0.200) 5/42 NT 23.5% intergenic (‑158/+109) yeeF/yeeY predicted amino‑acid transporter/predicted DNA‑binding transcriptional regulator
?REL606 3912266 = 91 (1.010)intergenic (+46/‑94) ilvL/ilvG ilvG operon leader peptide/acetolactate synthase II, valine insensitive, large subunit
* ? REL606 = 201768335 (0.340)14 (0.170) 3/38 NT 18.8% intergenic (‑178/+89) yeeF/yeeY predicted amino‑acid transporter/predicted DNA‑binding transcriptional regulator
?REL606 = 2919373 93 (1.140)intergenic (+6/+37) idi/lysS isopentenyl‑diphosphate delta‑isomerase/lysine tRNA synthetase, constitutive
* ? REL606 = 201988385 (0.830)18 (0.210) 5/40 NT 23.7% intergenic (‑312/‑115) yeeZ/hisL predicted epimerase, with NAD(P)‑binding Rossmann‑fold domain/his operon leader peptide
?REL606 = 3163334 45 (0.530)coding (1630/2352 nt) ygjK predicted glycosyl hydrolase
* ? REL606 2064681 =76 (0.740)9 (0.120) 3/36 NT 12.3% coding (596/1218 nt) wcaC predicted glycosyl transferase
?REL606 4179328 = 71 (0.920)coding (213/591 nt) yjaG hypothetical protein
* ? REL606 2064682 =77 (0.750)9 (0.110) 3/38 NT 10.8% coding (595/1218 nt) wcaC predicted glycosyl transferase
?REL606 = 3433062 88 (1.080)pseudogene (399/621 nt) yhfS putative enzyme; b3376_1
* ? REL606 2095315 =91 (0.890)5 (0.070) 3/34 NT 6.2% coding (744/1416 nt) yegB multidrug efflux system protein
?REL606 2237509 = 87 (1.200)intergenic (+34/+69) proL/yejO tRNA‑Pro/predicted autotransporter outer membrane protein
* ? REL606 = 213184671 (0.690)4 (0.040) 3/46 NT 7.0% coding (848/1053 nt) fbaB fructose‑bisphosphate aldolase
?REL606 2517490 = 38 (0.390)coding (76/864 nt) ypfJ hypothetical protein
* ? REL606 = 215149993 (0.910)15 (0.220) 5/32 NT 19.5% coding (25/3633 nt) yehI hypothetical protein
?REL606 = 2649902 NA (NA)noncoding (776/2906 nt) rrlG 23S ribosomal RNA
* ? REL606 2169426 =52 (0.510)13 (0.160) 6/38 NT 13.2% coding (329/1158 nt) yehY predicted transporter subunit: membrane component of ABC superfamily
?REL606 = 2730083 130 (1.600)coding (2203/2253 nt) hypF carbamoyl phosphate phosphatase and maturation protein for [NiFe] hydrogenases
* ? REL606 = 217501745 (0.440)18 (0.200) 5/42 NT 24.6% coding (1595/1716 nt) dld D‑lactate dehydrogenase, FAD‑binding, NADH independent
?REL606 = 4351424 71 (0.790)intergenic (+32/‑106) groEL/yjeI chaperonin GroEL/hypothetical protein
* ? REL606 2176060 =63 (0.610)6 (0.080) 3/36 NT 7.3% coding (49/933 nt) pbpG D‑alanyl‑D‑alanine endopeptidase
?REL606 3882315 = 105 (1.360)coding (103/816 nt) atpB F0F1 ATP synthase subunit A
* ? REL606 2183026 =73 (0.710)12 (0.160) 5/34 NT 15.2% intergenic (+74/‑56) yohK/cdd predicted inner membrane protein/cytidine deaminase
?REL606 = 3512380 82 (1.130)intergenic (‑122/‑211) yhhX/yhhY predicted oxidoreductase with NAD(P)‑binding Rossmann‑fold domain/predicted acetyltransferase
* ? REL606 = 219525778 (0.760)26 (0.260) 7/46 NT 26.7% coding (110/837 nt) yeiG predicted esterase
?REL606 2252861 = 71 (0.690)coding (142/264 nt) napD assembly protein for periplasmic nitrate reductase
* ? REL606 = 219525778 (0.760)27 (0.290) 5/44 NT 34.7% coding (110/837 nt) yeiG predicted esterase
?REL606 2888888 = 33 (0.320)coding (520/879 nt) xdhB xanthine dehydrogenase, FAD‑binding subunit
* ? REL606 = 219525778 (0.760)24 (0.240) 9/46 NT 29.1% coding (110/837 nt) yeiG predicted esterase
?REL606 = 4616836 44 (0.430)intergenic (+75/+232) nadR/yjjK nicotinamide‑nucleotide adenylyltransferase/fused predicted transporter subunits of ABC superfamily: ATP‑binding components
* ? REL606 = 219734985 (0.830)22 (0.240) 7/42 NT 18.7% coding (659/1992 nt) cirA ferric iron‑catecholate outer membrane transporter
?REL606 3882314 = 133 (1.290)coding (104/816 nt) atpB F0F1 ATP synthase subunit A
* ? REL606 = 220122361 (0.590)7 (0.090) 3/36 NT 9.6% coding (269/1050 nt) yeiH conserved inner membrane protein
?REL606 = 3512381 86 (1.120)intergenic (‑123/‑210) yhhX/yhhY predicted oxidoreductase with NAD(P)‑binding Rossmann‑fold domain/predicted acetyltransferase
* ? REL606 = 220422468 (0.660)16 (0.200) 4/38 NT 14.9% coding (1109/1251 nt) yeiJ predicted nucleoside transporter
?REL606 2724133 = 129 (1.590)coding (227/774 nt) srlR DNA‑bindng transcriptional repressor
* ? REL606 2216192 =62 (0.600)25 (0.310) 6/38 NT 27.2% coding (1142/1182 nt) setB lactose/glucose efflux system
?REL606 = 3911582 85 (1.040)coding (218/1551 nt) yifB predicted bifunctional enzyme and transcriptional regulator
* ? REL606 2234598 =88 (0.860)15 (0.180) 5/38 NT 16.6% coding (538/1008 nt) yejK nucleoid‑associated protein NdpA
?REL606 3944634 = 81 (1.000)intergenic (+23/‑124) proM/aslB tRNA‑Pro/predicted regulator of arylsulfatase activity
* ? REL606 2283386 =61 (0.590)10 (0.110) 3/44 NT 11.2% intergenic (‑42/+107) yfaA/gyrA hypothetical protein/DNA gyrase subunit A
?REL606 2645822 = 102 (1.080)coding (151/273 nt) yfiM hypothetical protein
* ? REL606 2288961 =52 (0.510)12 (0.140) 4/40 NT 19.0% coding (1909/3753 nt) yfaL adhesin
?REL606 = 3625456 59 (0.690)pseudogene (7/738 nt) yhjQ b3534; cell division protein (chromosome partitioning ATPase)
* ? REL606 2312280 =75 (0.730)5 (0.050) 3/44 NT 9.1% intergenic (‑147/‑143) ais/yfbE hypothetical protein/uridine 5'‑(beta‑1‑threo‑pentapyranosyl‑4‑ulose diphosphate) aminotransferase, PLP‑dependent
?REL606 = 4042610 31 (0.330)intergenic (‑57/+10) yshA/yihO predicted outer membrane porin L/predited transporter
* ? REL606 2318764 =63 (0.610)11 (0.140) 4/36 NT 13.6% coding (1344/1653 nt) arnT 4‑amino‑4‑deoxy‑L‑arabinose transferase
?REL606 4219145 = 92 (1.190)intergenic (+483/‑112) yjbH/yjbA predicted porin/phosphate‑starvation‑inducible protein PsiE
* ? REL606 2327674 =62 (0.600)14 (0.160) 5/42 NT 15.8% coding (383/462 nt) elaA predicted acyltransferase with acyl‑CoA N‑acyltransferase domain
?REL606 = 4527187 95 (1.060)coding (1178/2637 nt) fimD outer membrane usher protein, type 1 fimbrial synthesis
* ? REL606 = 234562869 (0.670)11 (0.120) 6/44 NT 10.6% coding (16/501 nt) nuoE NADH dehydrogenase subunit E
?REL606 3882315 = 123 (1.310)coding (103/816 nt) atpB F0F1 ATP synthase subunit A
* ? REL606 2377427 =84 (0.820)11 (0.120) 6/42 NT 16.1% coding (92/915 nt) accD acetyl‑CoA carboxylase subunit beta
?REL606 3367495 = 41 (0.460)intergenic (‑81/+26) yhdN/rplQ hypothetical protein/50S ribosomal protein L17
* ? REL606 2389861 =74 (0.720)12 (0.150) 5/38 NT 19.1% coding (116/825 nt) mepA penicillin‑insensitive murein endopeptidase
?REL606 = 2877079 43 (0.530)intergenic (‑276/+39) araE/kduD arabinose transporter/2‑deoxy‑D‑gluconate 3‑dehydrogenase
* ? REL606 = 245448167 (0.650)14 (0.140) 6/46 NT 15.1% coding (158/342 nt) ECB_02307 conserved hypothetical protein
?REL606 = 4471806 97 (0.940)coding (1485/1503 nt) yjgR predicted ATPase
* ? REL606 2487179 =54 (0.530)11 (0.170) 3/30 NT 21.0% coding (435/1404 nt) eutA reactivating factor for ethanolamine ammonia lyase
?REL606 = 3686151 49 (0.760)coding (411/741 nt) yiaT hypothetical protein
* ? REL606 = 253054466 (0.640)11 (0.120) 5/42 NT 18.2% coding (1232/1668 nt) hyfG hydrogenase 4, subunit
?REL606 3367495 = 41 (0.460)intergenic (‑81/+26) yhdN/rplQ hypothetical protein/50S ribosomal protein L17
* ? REL606 2532852 =62 (0.600)3 (0.040) 3/40 NT 4.7% coding (127/2007 nt) hyfR DNA‑binding transcriptional activator, formate sensing
?REL606 4530131 = 69 (0.810)coding (410/903 nt) fimH minor component of type 1 fimbriae
* ? REL606 2533712 =95 (0.920)9 (0.130) 3/32 NT 14.4% coding (987/2007 nt) hyfR DNA‑binding transcriptional activator, formate sensing
?REL606 3554407 = 44 (0.640)coding (321/384 nt) yhhH hypothetical protein
* ? REL606 2556110 =67 (0.650)14 (0.170) 5/38 NT 14.7% coding (1060/1371 nt) xseA exodeoxyribonuclease VII large subunit
?REL606 3882315 = 110 (1.350)coding (103/816 nt) atpB F0F1 ATP synthase subunit A
* ? REL606 = 2583271NA (NA)32 (0.530) 3/28 NT 49.9% intergenic (‑441/+11) iscR/yfhQ DNA‑binding transcriptional repressor/predicted methyltransferase
?REL606 = 3686161 55 (0.540)coding (401/741 nt) yiaT hypothetical protein
* ? REL606 2650606 =NA (NA)12 (0.190) 3/30 NT 17.1% noncoding (72/2906 nt) rrlG 23S ribosomal RNA
?REL606 = 2867475 93 (0.910)coding (1008/1194 nt) ygeD predicted inner membrane protein
* ? REL606 2671676 =67 (0.650)9 (0.120) 3/36 NT 13.7% coding (328/594 nt) grpE heat shock protein
?REL606 4487631 = 63 (0.820)coding (453/1119 nt) yjhC predicted oxidoreductase
* ? REL606 2682742 =NA (NA)39 (0.540) 6/34 NT 45.9% noncoding (135/768 nt) IS1 repeat region
?REL606 2703961 = 65 (0.630)coding (794/1185 nt) ygaX predicted transporter
* ? REL606 2698091 =73 (0.710)6 (0.070) 3/40 NT 9.3% coding (1992/2145 nt) nrdE ribonucleotide‑diphosphate reductase alpha subunit
?REL606 3668825 = 56 (0.650)coding (873/2031 nt) malS periplasmic alpha‑amylase precursor
* ? REL606 2703325 =45 (0.440)9 (0.120) 3/36 NT 16.6% coding (158/1185 nt) ygaX predicted transporter
?REL606 = 4091236 57 (0.740)coding (461/600 nt) yiiQ hypothetical protein
* ? REL606 2713428 =47 (0.520)102 (1.130) 38/42 NT 68.5% noncoding (77/93 nt) serV tRNA‑Ser
?REL606 = 2774196 NA (NA)noncoding (1343/1343 nt) IS186 repeat region
* ? REL606 = 2749601109 (1.060)21 (0.230) 6/42 NT 19.0% coding (404/2079 nt) fhlA DNA‑binding transcriptional activator
?REL606 4351442 = 84 (0.930)intergenic (+50/‑88) groEL/yjeI chaperonin GroEL/hypothetical protein
* ? REL606 2750665 =112 (1.090)16 (0.250) 4/30 NT 22.7% coding (1468/2079 nt) fhlA DNA‑binding transcriptional activator
?REL606 3792209 = 39 (0.610)coding (315/414 nt) ECB_03532 hypothetical protein
* ? REL606 = 2768160116 (1.130)20 (0.210) 7/44 NT 16.8% coding (39/324 nt) ygbE conserved inner membrane protein
?REL606 4085858 = 92 (0.980)intergenic (+56/‑93) cpxP/fieF periplasmic protein combats stress/ferrous iron efflux protein F
* ? REL606 = 278928365 (0.630)8 (0.080) 4/46 NT 11.2% coding (192/1278 nt) yqcE predicted transporter
?REL606 3161174 = 67 (0.650)coding (557/1071 nt) ygjJ hypothetical protein
* ? REL606 = 283622259 (0.570)12 (0.120) 7/46 NT 15.4% coding (29/396 nt) ygdD conserved inner membrane protein
?REL606 = 4349299 75 (0.760)intergenic (‑166/‑110) yjeH/groES predicted transporter/co‑chaperonin GroES
* ? REL606 2840701 =74 (0.720)27 (0.270) 8/46 NT 24.4% coding (1097/1098 nt) mltA membrane‑bound lytic murein transglycosylase A
?REL606 3891539 = 96 (0.970)intergenic (‑85/‑138) yieN/kup fused predicted transcriptional regulator: sigma54 activator protein/conserved protein/potassium transporter
* ? REL606 2880569 =60 (0.580)11 (0.140) 4/36 NT 19.1% coding (101/1230 nt) yqeG predicted transporter
?REL606 3287064 = 48 (0.620)coding (1197/2337 nt) arcB hybrid sensory histidine kinase in two‑component regulatory system with ArcA
* ? REL606 = 288132343 (0.420)10 (0.130) 4/36 NT 12.7% coding (855/1230 nt) yqeG predicted transporter
?REL606 3882315 = 105 (1.360)coding (103/816 nt) atpB F0F1 ATP synthase subunit A
* ? REL606 = 2883502NA (NA)22 (0.270) 4/38 NT 28.1% noncoding (791/1255 nt) IS3 repeat region
?REL606 3001880 = 71 (0.690)coding (2317/2847 nt) flu antigen 43 (Ag43) phase‑variable biofilm formation autotransporter
* ? REL606 = 290073192 (0.900)9 (0.110) 3/40 NT 13.3% coding (82/771 nt) yqeC hypothetical protein
?REL606 4370910 = 41 (0.480)intergenic (+97/+173) glyY/yjeS tRNA‑Gly/predicted Fe‑S electron transport protein
* ? REL606 2908068 =60 (0.580)9 (0.110) 4/38 NT 14.3% coding (999/2871 nt) xdhD fused predicted xanthine/hypoxanthine oxidase: molybdopterin‑binding subunit/Fe‑S binding subunit
?REL606 4123539 = 60 (0.740)coding (903/1080 nt) frwC predicted enzyme IIC component of PTS
* ? REL606 2926199 =70 (0.680)14 (0.180) 5/36 NT 18.0% coding (378/408 nt) ygfX hypothetical protein
?REL606 3944634 = 75 (0.970)intergenic (+23/‑124) proM/aslB tRNA‑Pro/predicted regulator of arylsulfatase activity
* ? REL606 2933125 =46 (0.450)11 (0.140) 5/38 NT 16.9% coding (1669/2874 nt) gcvP glycine dehydrogenase
?REL606 = 3606341 72 (0.890)coding (1517/2076 nt) yhjG predicted outer membrane biogenesis protein
* ? REL606 = 294481647 (0.460)22 (0.210) 8/48 NT 22.6% coding (261/660 nt) rpiA ribose‑5‑phosphate isomerase A
?REL606 3912264 = 104 (1.010)intergenic (+44/‑96) ilvL/ilvG ilvG operon leader peptide/acetolactate synthase II, valine insensitive, large subunit
* ? REL606 = 294957169 (0.670)15 (0.150) 5/46 NT 14.6% coding (834/996 nt) argK arginine/ornithine transport system ATPase
?REL606 = 3728925 109 (1.110)coding (59/960 nt) yibQ predicted polysaccharide deacetylase
* ? REL606 2962019 =71 (0.690)12 (0.160) 4/34 NT 19.5% coding (1189/1278 nt) yggP predicted dehydrogenase
?REL606 3792210 = 49 (0.670)coding (316/414 nt) ECB_03532 hypothetical protein
* ? REL606 2966042 =52 (0.510)5 (0.060) 3/36 NT 9.1% coding (1345/1992 nt) tktA transketolase 1, thiamin‑binding
?REL606 3780481 = 61 (0.790)coding (513/1359 nt) ECB_03520 conserved hypothetical protein
* ? REL606 = 296632071 (0.690)9 (0.120) 3/36 NT 10.0% coding (1067/1992 nt) tktA transketolase 1, thiamin‑binding
?REL606 3882316 = 109 (1.410)coding (102/816 nt) atpB F0F1 ATP synthase subunit A
* ? REL606 = 2979870135 (1.310)6 (0.060) 3/44 NT 6.2% coding (962/981 nt) yggR predicted transporter
?REL606 4245169 = 59 (0.630)coding (456/1080 nt) alr alanine racemase
* ? REL606 = 298140148 (0.470)13 (0.170) 5/36 NT 15.6% coding (553/705 nt) yggS predicted enzyme
?REL606 3882315 = 105 (1.360)coding (103/816 nt) atpB F0F1 ATP synthase subunit A
* ? REL606 2998284 =85 (0.830)9 (0.110) 4/40 NT 12.9% intergenic (+49/‑483) ECB_02798/yeeP conserved hypothetical protein/b1999; predicted GTP‑binding protein
?REL606 3832612 = 51 (0.600)coding (748/1149 nt) dgoD galactonate dehydratase
* ? REL606 3006451 =87 (0.850)9 (0.100) 4/44 NT 11.8% coding (461/819 nt) yafZ conserved protein
?REL606 4115747 = 55 (0.580)coding (1806/2181 nt) katG catalase/hydroperoxidase HPI(I)
* ? REL606 3016826 =44 (0.430)12 (0.160) 5/36 NT 14.8% coding (561/741 nt) ECB_02817 KpsU protein
?REL606 3882315 = 105 (1.360)coding (103/816 nt) atpB F0F1 ATP synthase subunit A
* ? REL606 = 304063893 (0.910)11 (0.140) 3/38 NT 14.8% coding (649/810 nt) pppA bifunctional prepilin leader peptidase/ methylase
?REL606 4567447 = 53 (0.650)coding (1808/2151 nt) yjiY predicted inner membrane protein
* ? REL606 = 304063997 (0.940)17 (0.220) 5/36 NT 21.2% coding (648/810 nt) pppA bifunctional prepilin leader peptidase/ methylase
?REL606 3224905 = 54 (0.700)coding (858/2517 nt) yraJ predicted outer membrane protein
* ? REL606 = 306962169 (0.670)12 (0.140) 4/40 NT 17.1% coding (838/1500 nt) pitB phosphate transporter
?REL606 = 3625456 59 (0.690)pseudogene (7/738 nt) yhjQ b3534; cell division protein (chromosome partitioning ATPase)
* ? REL606 3092326 =61 (0.590)23 (0.240) 8/44 NT 23.7% coding (505/927 nt) yqhG hypothetical protein
?REL606 4085858 = 92 (0.980)intergenic (+56/‑93) cpxP/fieF periplasmic protein combats stress/ferrous iron efflux protein F
* ? REL606 3182813 =111 (1.080)7 (0.110) 3/30 NT 10.7% coding (97/405 nt) yqjE conserved inner membrane protein
?REL606 4217451 = 48 (0.750)coding (886/2097 nt) yjbH predicted porin
* ? REL606 3190470 =58 (0.560)12 (0.120) 5/46 NT 19.7% coding (511/1269 nt) yhaO predicted transporter
?REL606 4585732 = 42 (0.430)coding (509/1023 nt) yjjN predicted oxidoreductase, Zn‑dependent and NAD(P)‑binding
* ? REL606 3258154 =65 (0.630)8 (0.110) 5/34 NT 13.0% coding (1151/1338 nt) glmM phosphoglucosamine mutase
?REL606 3281934 = 61 (0.840)coding (122/492 nt) ptsN sugar‑specific enzyme IIA component of PTS
* ? REL606 3265224 =32 (0.310)6 (0.070) 3/38 NT 9.0% coding (1028/1434 nt) dacB D‑alanyl‑D‑alanine carboxypeptidase
?REL606 = 3603631 96 (1.180)coding (778/1014 nt) yhjD conserved inner membrane protein
* ? REL606 3281469 =113 (1.100)21 (0.220) 7/44 NT 18.2% coding (62/288 nt) yhbH predicted ribosome‑associated, sigma 54 modulation protein
?REL606 = 4043982 85 (0.900)coding (42/1404 nt) yihO predited transporter
* ? REL606 3302668 =53 (0.520)10 (0.120) 6/38 NT 13.9% intergenic (‑281/‑99) nanR/dcuD transcriptional regulator NanR/predicted transporter
?REL606 4085857 = 82 (1.010)intergenic (+55/‑94) cpxP/fieF periplasmic protein combats stress/ferrous iron efflux protein F
* ? REL606 = 331092177 (0.750)8 (0.110) 3/34 NT 15.0% coding (824/1068 nt) degS serine endoprotease, periplasmic
?REL606 4603001 = 36 (0.490)coding (287/780 nt) yjjV predicted DNase
* ? REL606 = 3320231NA (NA)11 (0.180) 3/28 NT 25.5% intergenic (‑312/+118) tldD/yhdP predicted peptidase/conserved membrane protein, predicted transporter
?REL606 = 3686161 55 (0.540)coding (401/741 nt) yiaT hypothetical protein
* ? REL606 3331631 =78 (0.760)5 (0.070) 4/34 NT 9.4% coding (257/975 nt) yhdH predicted oxidoreductase, Zn‑dependent and NAD(P)‑binding
?REL606 = 4600665 41 (0.560)coding (36/606 nt) osmY periplasmic protein
* ? REL606 3411408 =52 (0.510)21 (0.310) 4/32 NT 37.7% coding (302/1023 nt) yheT predicted hydrolase
?REL606 3433812 = NA (NA)noncoding (418/768 nt) IS1 repeat region
* ? REL606 3476747 =59 (0.570)10 (0.120) 3/38 NT 12.0% coding (1924/2085 nt) malQ 4‑alpha‑glucanotransferase (amylomaltase)
?REL606 4031309 = 100 (1.230)coding (968/1374 nt) hemN coproporphyrinogen III oxidase
* ? REL606 3483684 =62 (0.600)11 (0.140) 5/36 NT 15.9% coding (2000/2706 nt) malT transcriptional regulator MalT
?REL606 = 3677027 70 (0.910)coding (478/987 nt) yiaO predicted transporter
* ? REL606 = 351749069 (0.670)13 (0.130) 8/48 NT 14.7% coding (10/1743 nt) ggt gamma‑glutamyltranspeptidase periplasmic precursor
?REL606 = 4266659 82 (0.800)intergenic (‑355/‑38) acs/nrfA acetyl‑coenzyme A synthetase/nitrite reductase, formate‑dependent, cytochrome
* ? REL606 = 354520181 (0.790)9 (0.120) 3/36 NT 13.7% coding (847/1575 nt) nikA nickel transporter subunit
?REL606 = 4576439 53 (0.690)coding (2/381 nt) hpaF 5‑carboxymethyl‑2‑hydroxymuconate delta‑isomerase
* ? REL606 3579044 =7 (0.070)29 (0.320) 6/42 NT 37.4% intergenic (+703/‑174) gor/arsR glutathione reductase/DNA‑binding transcriptional repressor
?REL606 3912266 = 91 (1.010)intergenic (+46/‑94) ilvL/ilvG ilvG operon leader peptide/acetolactate synthase II, valine insensitive, large subunit
* ? REL606 3600745 =41 (0.400)9 (0.120) 3/34 NT 18.7% intergenic (+12/+39) treF/yhjB cytoplasmic trehalase/predicted DNA‑binding response regulator in two‑component regulatory system
?REL606 3792210 = 49 (0.670)coding (316/414 nt) ECB_03532 hypothetical protein
* ? REL606 3615477 =121 (1.180)11 (0.110) 4/48 NT 10.1% coding (3189/3474 nt) bcsC cellulose synthase subunit
?REL606 = 3947083 74 (0.720)coding (724/1656 nt) aslA acrylsulfatase‑like enzyme
* ? REL606 = 362546064 (0.620)22 (0.260) 7/40 NT 30.7% pseudogene (3/738 nt) yhjQ b3534; cell division protein (chromosome partitioning ATPase)
?REL606 = 3992020 46 (0.540)coding (141/510 nt) ECB_03720 conserved hypothetical protein
* ? REL606 = 3630716NA (NA)79 (0.770) 38/48 NT NA intergenic (‑171/‑305) ldrD/yhjV toxic polypeptide, small/predicted transporter
?REL606 = 3652533 NA (NA)noncoding (1443/1443 nt) IS150 repeat region
* ? REL606 3656754 =92 (0.900)4 (0.070) 3/28 NT 7.1% coding (410/996 nt) yiaH conserved inner membrane protein
?REL606 = 4045305 51 (0.850)coding (165/1407 nt) yihP predicted transporter
* ? REL606 = 3676501106 (1.030)13 (0.130) 7/46 NT 12.1% coding (1242/1278 nt) yiaN predicted transporter
?REL606 = 3822225 91 (0.890)coding (203/1323 nt) glvG predicted 6‑phospho‑beta‑glucosidase
* ? REL606 = 368615255 (0.540)7 (0.070) 3/46 NT 10.7% coding (410/741 nt) yiaT hypothetical protein
?REL606 = 4031953 64 (0.650)intergenic (+238/+174) hemN/glnG coproporphyrinogen III oxidase/fused DNA‑binding response regulator in two‑component regulatory system with GlnL: response regulator/sigma54 interaction protein
* ? REL606 = 368616056 (0.540)10 (0.160) 3/30 NT 30.3% coding (402/741 nt) yiaT hypothetical protein
?REL606 4048325 = 11 (0.170)coding (224/927 nt) yihR predicted aldose‑1‑epimerase
* ? REL606 = 368616056 (0.540)23 (0.230) 5/46 NT 30.0% coding (402/741 nt) yiaT hypothetical protein
?REL606 = 4467594 NA (NA)intergenic (‑281/+73) holC/pepA DNA polymerase III subunit chi/leucyl aminopeptidase
* ? REL606 3698836 =NA (NA)15 (0.210) 4/34 NT 13.9% coding (1960/4134 nt) rhsA rhsA element core protein RshA
?REL606 3882308 = 131 (1.270)coding (110/816 nt) atpB F0F1 ATP synthase subunit A
* ? REL606 = 370493571 (0.690)362 (5.280) 9/32 NT 88.4% intergenic (+1603/+1) yibG/yibH hypothetical protein/hypothetical protein
?REL606 = 3741809 NA (NA)noncoding (157/768 nt) IS1 repeat region
* ? REL606 = 3741965NA (NA)80 (0.780) 37/48 NT 93.0% noncoding (1/768 nt) IS1 repeat region
?REL606 3742143 = 6 (0.060)pseudogene (223/405 nt) waaT UDP‑galactose:(Glucosyl) LPS alpha1,2‑galactosyltransferase WaaT
* ? REL606 = 3744020103 (1.000)12 (0.160) 5/36 NT 18.0% coding (300/807 nt) waaP kinase that phosphorylates core heptose of lipopolysaccharide
?REL606 = 3861481 32 (0.420)coding (1109/1617 nt) yieC carbohydrate‑specific outer membrane porin, cryptic
* ? REL606 = 375752576 (0.740)22 (0.260) 8/40 NT 23.1% coding (295/618 nt) yicG conserved inner membrane protein
?REL606 4085859 = 83 (0.970)intergenic (+57/‑92) cpxP/fieF periplasmic protein combats stress/ferrous iron efflux protein F
* ? REL606 3780471 =81 (0.790)7 (0.120) 4/28 NT 14.0% coding (503/1359 nt) ECB_03520 conserved hypothetical protein
?REL606 = 4600662 39 (0.650)coding (33/606 nt) osmY periplasmic protein
* ? REL606 3809862 =86 (0.840)7 (0.100) 4/34 NT 8.2% coding (207/1503 nt) uhpB sensory histidine kinase in two‑component regulatory sytem with UhpA
?REL606 3882315 = 96 (1.320)coding (103/816 nt) atpB F0F1 ATP synthase subunit A
* ? REL606 3820609 =84 (0.820)7 (0.100) 3/34 NT 12.1% coding (425/924 nt) yidL predicted DNA‑binding transcriptional regulator
?REL606 = 4248913 42 (0.580)coding (568/714 nt) aphA acid phosphatase/phosphotransferase, class B, non‑specific
* ? REL606 3826321 =43 (0.420)5 (0.060) 3/42 NT 9.5% coding (314/1662 nt) yidE hypothetical protein
?REL606 = 3885956 58 (0.650)coding (39/1890 nt) gidA glucose‑inhibited division protein A
* ? REL606 = 386696686 (0.840)18 (0.180) 8/46 NT 20.6% intergenic (‑32/+254) bglG/phoU transcriptional antiterminator of the bgl operon/negative regulator of PhoR/PhoB two‑component regulator
?REL606 = 3887469 56 (0.570)intergenic (‑105/‑47) asnC/asnA DNA‑binding transcriptional dual regulator/asparagine synthetase AsnA
* ? REL606 = 3894996NA (NA)5 (0.050) 5/46 NT 5.3% noncoding (1443/1443 nt) IS150 repeat region
?REL606 = 4415712 90 (0.910)coding (850/1413 nt) cycA D‑alanine/D‑serine/glycine transporter
* ? REL606 3944627 =101 (0.980)9 (0.120) 3/34 NT 13.8% intergenic (+16/‑131) proM/aslB tRNA‑Pro/predicted regulator of arylsulfatase activity
?REL606 = 4275759 41 (0.560)coding (189/690 nt) yjcO hypothetical protein
* ? REL606 4085856 =100 (0.970)24 (0.250) 5/44 NT 23.2% intergenic (+54/‑95) cpxP/fieF periplasmic protein combats stress/ferrous iron efflux protein F
?REL606 4214283 = 67 (0.710)coding (1595/1650 nt) pgi glucose‑6‑phosphate isomerase
* ? REL606 = 408655471 (0.690)6 (0.070) 5/42 NT 6.5% coding (604/903 nt) fieF ferrous iron efflux protein F
?REL606 4620932 = 111 (1.230)intergenic (+49/‑41) slt/trpR lytic murein transglycosylase, soluble/Trp operon repressor
* ? REL606 = 415489872 (0.700)7 (0.080) 5/42 NT 8.7% intergenic (‑261/‑101) coaA/thrU pantothenate kinase/tRNA‑Thr
?REL606 4351442 = 84 (0.930)intergenic (+50/‑88) groEL/yjeI chaperonin GroEL/hypothetical protein
* ? REL606 = 418706983 (0.810)13 (0.170) 5/36 NT 15.8% coding (49/1590 nt) purH bifunctionalphosphoribosylaminoimidazolecarboxam ide formyltransferase/IMP cyclohydrolase
?REL606 = 4402608 76 (0.990)intergenic (+67/+62) sgaE/yjfY L‑ribulose 5‑phosphate 4‑epimerase/hypothetical protein
* ? REL606 = 4551446NA (NA)9 (0.090) 8/46 NT 7.0% noncoding (768/768 nt) IS1 repeat region
?REL606 4560889 = 119 (1.210)coding (135/1590 nt) hsdM DNA methylase M